abstract：:The reasons for the rise in autism prevalence are a subject of heated professional debate. Featuring a critical appraisal of some research used to question whether rising levels of autism are related to environmental exposure to toxins (Soden et al. 2007, Barbaresi et al. 2009, Thompson et al. 2007) we aim to evaluate...

journal_title：Acta neurobiologiae experimentalis

authors： Desoto MC,Hitlan RT

更新日期：2010-01-01 00:00:00

abstract：:A subdivided path in the visual field usually appears longer than an empty path of the same length. This phenomenon, known as the filled/empty or Oppel-Kundt illusion, depends on multiple properties of the visual stimulus, but the functional dependences have not been yet precisely characterized. We studied the illusor...

journal_title：Acta neurobiologiae experimentalis

authors： Wackermann J,Kastner K

更新日期：2010-01-01 00:00:00

abstract：:Working memory is an ability to keep information in short-term memory and manipulate them 'on line'. Working memory is also involved in complex frontal executive functions. The role of dopaminergic system in modulating working memory processes in prefrontal cortex is well established. Also the role of serotoninergic r...

journal_title：Acta neurobiologiae experimentalis

authors： Wiłkość M,Hauser J,Tomaszewska M,Dmitrzak-Weglarz M,Skibińska M,Szczepankiewicz A,Borkowska A

更新日期：2010-01-01 00:00:00

abstract：:The evoked cardiac response (ECR) may be described as the sum of two independent response components: an initial HR deceleration (ECR1) and a slightly later acceleration (ECR2) hypothesized to reflect stimulus registration and cognitive processing load, respectively. This study investigated processing load effects in ...

journal_title：Acta neurobiologiae experimentalis

authors： Lawrence CA,Barry RJ

更新日期：2009-01-01 00:00:00

abstract：:The noble gas xenon (Xe) inhibits not only NMDA receptors (NMDARs) but also the two other subtypes of glutamate receptor i.e. AMPA (AMPARs) and kainate receptors. Preliminary studies on AMPARs suggest that Xe sensitivity might be coupled to receptor desensitization. In order to find out if this hypothesis can be appli...

journal_title：Acta neurobiologiae experimentalis

authors： Weigt HU,Fohr KJ,Georgieff M,Georgieff EM,Senftleben U,Adolph O

更新日期：2009-01-01 00:00:00

abstract：:The neurocognitive consequences of correct or incorrect spatial prediction in a sequential S1-S2 paradigm were assessed. Sequential dependence on previous trial outcome (valid or invalid) was assessed by late Event-Related Potentials (ERPs) and behavioral responses. Two different experiments were performed, situating ...

journal_title：Acta neurobiologiae experimentalis

authors： Gómez CM,Flores A,Digiacomo MR,Vázquez-Marrufo M

更新日期：2009-01-01 00:00:00

abstract：:The finding of stem/progenitor cells in postnatal bone marrow and umbilical cord blood, opens up a possibility of using stem cells to treat neurologic diseases. There is a controversy, whether intravenously administered human umbilical cord blood cells (HUCBC) migrate to the brain, differentiate and improve recovery a...

journal_title：Acta neurobiologiae experimentalis

authors： Zawadzka M,Lukasiuk K,Machaj EK,Pojda Z,Kamińska B

更新日期：2009-01-01 00:00:00

abstract：:The objective of this study was to verify hypothesised changes in event related potentials (visual mismatch negativity, vMMN) in 17 subjects dependent on methamphetamine (MAMP) compared to age and gender matched 17 healthy volunteers. We found a significant correlation between vMMN and duration of methamphetamine abus...

journal_title：Acta neurobiologiae experimentalis

authors： Hosak L,Kremlacek J,Kuba M,Libiger J,Cizek J

更新日期：2008-01-01 00:00:00

abstract：:Our work assesses the effects of mu opioid receptor activation on high-threshold Ca2+/Ba2+ currents in freshly dispersed pyramidal neurons of the medial prefrontal cortex in rats. Application of the specific mu receptor agonist (D-Ala2+, N-Me-Phe4+, Gly5+-ol)-enkephalin (DAMGO) at 1 microM decreased Ca2+ current ampli...

journal_title：Acta neurobiologiae experimentalis

authors： Rola R,Jarkiewicz M,Szulczyk P

更新日期：2008-01-01 00:00:00

abstract：:Temporal information processing controls many aspects of human mental activity and may be assessed by examining perception of temporal order in the tens of milliseconds time range. Although existing studies suggest an age-related decline in mental abilities, the data on the deterioration of temporal order perception s...

journal_title：Acta neurobiologiae experimentalis

authors： Kołodziejczyk I,Szelsg E

更新日期：2008-01-01 00:00:00

abstract：:Signal integration in neurons is a complex process that depends on e.g. the kinetics of synaptic currents, distribution of synaptic connections as well as passive and excitatory membrane properties. The time course of synaptic currents is largely determined by the kinetics of the postsynaptic receptors and the time co...

journal_title：Acta neurobiologiae experimentalis

authors： Mozrzymas JW

更新日期：2008-01-01 00:00:00

abstract：:Quercetin, one of the major flavonoids, exhibits many beneficial effects on human organism as antihistamine, antioxidant, anti-inflammatory, anticancer and antiviral drug. It is recommended as supplement of healthy diet but still the knowledge of its beneficial effect on normal cells is not satisfactory. We decided to...

journal_title：Acta neurobiologiae experimentalis

authors： Jakubowicz-Gil J,Rzeski W,Zdzisinska B,Dobrowolski P,Gawron A

更新日期：2008-01-01 00:00:00

abstract：:The frequency of obturator nerve damage due to pelvic diseases, fractures or gynecologic procedures is uncertain. In the present study, we investigated the effect of FK506, a potent macrolide antibiotic and immunosuppresant, on obturator nerve recovery at morphological and functional levels. Forty female Wistar rats w...

journal_title：Acta neurobiologiae experimentalis

authors： Yildirim FB,Sarikcioglu L,Ozsoy U,Demir N,Demirtop A,Ucar Y

更新日期：2008-01-01 00:00:00

abstract：:Cholinesterase inhibitors are currently the mainstream of symptomatic treatment of patients with Alzheimer's disease. The response to treatment with cholinesterase inhibitors is clinically difficult to predict. Several demographic, clinical and biological variables have been proposed as pretreatment predictors of long...

journal_title：Acta neurobiologiae experimentalis

authors： Sobow T,Flirski M,Liberski P,Kloszewska I

更新日期：2007-01-01 00:00:00

abstract：:Recent development of neuroimaging techniques has opened new possibilities for the study of the relation between handedness and the brain functional architecture. Here we report fMRI measurements of dominant and non-dominant hand movement representation in 12 right-handed subjects using block design. We measured possi...

journal_title：Acta neurobiologiae experimentalis

authors： Gut M,Urbanik A,Forsberg L,Binder M,Rymarczyk K,Sobiecka B,Kozub J,Grabowska A

更新日期：2007-01-01 00:00:00

abstract：:This study describes the topography, borders and divisions of the globus pallidus in the Brazilian short-tailed opossum (Monodelphis domestica) and distribution of the three calcium binding proteins, parvalbumin (PV), calbindin D-28k (CB) and calretinin (CR) in that nucleus. The globus pallidus of the opossum consists...

journal_title：Acta neurobiologiae experimentalis

authors： Domaradzka-Pytel B,Majak K,Spodnik J,Olkowicz S,Turlejski K,Djavadian RL,Moryś J

更新日期：2007-01-01 00:00:00

abstract：:Human umbilical cord blood (HUCB) is considered a promising source of neural progenitors capable of being used for cellular therapies in neurological disorders. Here we review briefly our work on the elucidation of mechanisms and development of practical standards as regards the selection, maintenance and use of cord ...

journal_title：Acta neurobiologiae experimentalis

authors： Domanska-Janik K,Habich A,Sarnowska A,Janowski M

更新日期：2006-01-01 00:00:00

abstract：:There have been four major pioneers from Eastern Europe in the neuroscientific study of memory and learning: Pavlov, Bekhterev, Beritashvili and Konorski. The thinking of each evolved with the progress of neuroscientific knowledge throughout the world, and save for Pavlov, each encountered governmental opposition to t...

journal_title：Acta neurobiologiae experimentalis

authors： Doty RW

更新日期：2006-01-01 00:00:00

abstract：:In WAG/Rij rats the pair linear correlation r was calculated for bipolar recordings in fronto-temporal, fronto-occipital and occipito-temporal zones of both hemispheres as well as in paleocerebellar cortex (culmen). It was shown that development of SWD bursts resulted in interhemispheric decreases of correlation betwe...

journal_title：Acta neurobiologiae experimentalis

authors： Godlevsky LS,Vostrov GN,Kobolev EV,van Luijtelaar EL,Coenen AM,Iorhachova MN,Pereverzev VA,Smirnov IV

更新日期：2006-01-01 00:00:00

abstract：:Neuron transplantation is considered to be a promising therapeutic method to replace functions lost due to central nervous system (CNS) damage. However, little is known about the extent to which implanted neuron-like cells can develop into mature neurons and acquire essential properties, and especially formation of sy...

journal_title：Acta neurobiologiae experimentalis

authors： Zhou T,Xu B,Que H,Lin Q,Lv S,Liu S

更新日期：2006-01-01 00:00:00

abstract：:The paralytic tremor (pt) disease in rabbits results from a point mutation in a plp gene and manifests itself by a broad range of neurological signs. Biochemical studies have shown that myelinogenesis is retarded and deficient in mutant rabbits. Myelin sheaths are usually thin and malformed. The number of oligodendroc...

journal_title：Acta neurobiologiae experimentalis

authors： Sypecka J,Domańska-Janik K

更新日期：2005-01-01 00:00:00

abstract：:The Sgt1 protein was discovered in yeast but later it was found in other eucaryotic organisms, including plants and mammals. It was suggested that the Sgt1 protein plays a role in the CBF3 kinetochore and the SCF ubiquitin ligase complexes. Since the distribution, properties and functions of the mammalian Sgt1 have no...

journal_title：Acta neurobiologiae experimentalis

authors： Spiechowicz M,Filipek A

更新日期：2005-01-01 00:00:00

abstract：:New features of actual choice behavior and effortful information processing in rats were demonstrated in an eight-arm radial maze through modifications of a matching-to-sample task. Two attempts were allowed for a squad of hooded Sprague-Dawley rats (n=7) for finding a reward in a testing phase of the task. The result...

journal_title：Acta neurobiologiae experimentalis

authors： Stolberg A

更新日期：2005-01-01 00:00:00

abstract：:In psychophysical experiments, subjects matched two spatial intervals of a three-spot stimulus into what appeared to them to be equal. The stimulus was flanked by stripes. The length matching errors increased in proportion to the referent interval of the stimulus and approached 6-12 percent of its length. Also, the er...

journal_title：Acta neurobiologiae experimentalis

authors： Bulatov A,Bertulis A

更新日期：2005-01-01 00:00:00

abstract：:The pedunculopontine tegmental nucleus (PPN) is one of the reticular generators of the hippocampal theta rhythm. The PPN neuronal circuitry related to theta generation involves its cholinergic, GABA-ergic and glutamatergic components. Here we provide data indicating that the PPN tachykinin system may also be a part of...

journal_title：Acta neurobiologiae experimentalis

authors： Leszkowicz E,Trojniar W

更新日期：2005-01-01 00:00:00

abstract：:Abnormal auditory temporal processing might be an underlying deficit in language disabilities. The auditory temporal-order threshold, one measure for temporal processing abilities, is defined as the shortest time interval between two acoustic events necessary for a person to be able to identify the correct temporal or...

journal_title：Acta neurobiologiae experimentalis

authors： Berwanger D,Wittmann M,von Steinbüchel N,von Suchodoletz W

更新日期：2004-01-01 00:00:00

abstract：:Anxiety and depression have dramatic impact on human and animal behaviors. We take an interdisciplinary approach and review the existing experimental models of anxiety and depression in order to promote further understanding of neurobiological aspects of anxiety and depression. ...

journal_title：Acta neurobiologiae experimentalis

authors： Kalueff AV,Tuohimaa P

更新日期：2004-01-01 00:00:00

abstract：:We describe a method for generating and presenting olfactory stimuli in functional magnetic resonance imaging (fMRI) studies for humans. The olfactometer is based on principles of air dilution olfactometry and consists of a nasal mask and a nasal Continuous Positive Airway Pressure device, both normally used for patie...

journal_title：Acta neurobiologiae experimentalis

authors： Popp R,Sommer M,Müller J,Hajak G

更新日期：2004-01-01 00:00:00

abstract：:With the development of new therapeutic strategies, and the concept of mild cognitive impairment (MCI) as an early stage of Alzheimer's disease (AD), there is an increasing need for an early and accurate diagnosis of sporadic AD. Therefore, biological markers allowing a positive diagnosis early in the course of the di...

journal_title：Acta neurobiologiae experimentalis

authors： Sobów T,Flirski M,Liberski PP

更新日期：2004-01-01 00:00:00

abstract：:The aim of the present study was to investigate the effect of small unilateral lesions to the ventromedial portion of the prefrontal cortex on two memory functions: memory for objects and memory for object locations. Patients, who had undergone surgery of the anterior communicating artery aneurysm, and normal control ...

journal_title：Acta neurobiologiae experimentalis

authors： Szatkowska I,Grabowska A,Szymańska O

更新日期：2003-01-01 00:00:00

abstract：:This mini review gives a brief overview over the oxidation mechanism of methionine (Met), relevant for processes which may lead to the oxidation of amyloid beta-peptide (betaAP), involved in the pathogenesis of Alzheimer's disease. The Cu(II) -catalysed oxidation of C-terminal Met35 in betaAP depends on the secondary ...

journal_title：Acta neurobiologiae experimentalis

authors： Pogocki D

更新日期：2003-01-01 00:00:00

abstract：:Synapsins are a family of proteins associated with synaptic vesicles that are widely used as markers of synaptic terminals. We decided to investigate synapsin I expression in the mouse primary somatosensory cortex (SI). Immunostaining experiments using a polyclonal antibody against C-terminal domain of synapsin Ia/b (...

journal_title：Acta neurobiologiae experimentalis

authors： Nowicka D,Liguz-Lecznar M,Skangiel-Kramska J

更新日期：2003-01-01 00:00:00

abstract：:It was found previously that unilateral destruction of the ventral tegmental area (VTA) facilitated behavioral responses (exploration, eating) induced by electrical stimulation of the contralateral VTA. The same effect occurred after unilateral injections of pharmacological agents, which led to a decrease in dopaminer...

journal_title：Acta neurobiologiae experimentalis

authors： Jurkowlaniec E,Tokarski J,Trojniar W

更新日期：2003-01-01 00:00:00

abstract：:The aim of the study was to evaluate REM sleep parameters, especially the temporal characteristics of rapid eye movement activity, in depressed patients, and to compare three different methods for scoring of REM density. The sleep of 15 nonmedicated depressed patients and 13 healthy controls was recorded during two co...

journal_title：Acta neurobiologiae experimentalis

authors： Wichniak A,Antczak J,Wierzbicka A,Jernajczyk W

更新日期：2002-01-01 00:00:00

abstract：:Twenty-two rats were reared in standard conditions during the first two months of their life. Then the animals were divided into two groups exposed to different rearing conditions. Twelve animals (Group SO) were housed socially, six animals per cage, and for three weeks they were subjected to sensory stimulation in an...

journal_title：Acta neurobiologiae experimentalis

authors： Walasek G,Wesierska M,Werka T

更新日期：2002-01-01 00:00:00

abstract：:We report here the microglial (macrophage) and astrocytic reaction in several models of transmissible spongiform encephalopathies (TSEs) or prion diseases. With the low power electron microscopy it was readily apparent that myelinated vacuoles were surrounded by cells and their processes. The latter belonged either to...

journal_title：Acta neurobiologiae experimentalis

authors： Liberski PP,Bratosiewicz-Wasik J,Gajdusek DC,Brown P

更新日期：2002-01-01 00:00:00

abstract：:Earlier in vivo studies conducted on freely moving and anesthetized rats demonstrated that the posterior hypothalamus (PH) comprises pathways critical for producing the synchronous hippocampal formation (HPC) theta rhythm. In addition, these findings suggested that the frequency of the HPC theta was encoded in the PH ...

journal_title：Acta neurobiologiae experimentalis

authors： Bocian R,Konopacki J

更新日期：2001-01-01 00:00:00

abstract：:A immunohistochemical study of postnatal development of the paraclaustral reservoir of migrating cells in the rat brain was performed using anti-GFAP (for astroglia), ED1 and OX-42 (for microglia) antibodies. From birth to the 4th day of postnatal life most GFAP-positive cells in the paraclaustral reservoir are simila...

journal_title：Acta neurobiologiae experimentalis

authors： Ludkiewicz B,Domaradzka-Pytel B,Moryś J

更新日期：2001-01-01 00:00:00

abstract：:The variability of simple actions with response to auditory stimuli was studied under different delay conditions. Subjects reacted as fast as possible or with a defined time delay (from 250 to 750 ms) to a tone switching off by pressing a response-key with the left index finger (controlled by the right hemisphere) or ...

journal_title：Acta neurobiologiae experimentalis

authors： Szelaģ E,Rymarczyk K,Pöppel E

更新日期：2001-01-01 00:00:00

abstract：:The effect of central, short-term melatonin administration on daily GnRH and LH secretion was studied in ewes during seasonal anestrus. Melatonin, in a total dose of 32 micrograms and the vehicle were perfused for 4 hours into the mediobasal hypothalamus/median eminence (MBH/ME). The mean GnRH concentration during per...

journal_title：Acta neurobiologiae experimentalis

authors： Romanowicz K,Misztal T,Gajewska A,Barcikowski B

更新日期：2001-01-01 00:00:00